Search results for : flt3 - Cancerrxgene - Genomics of Drug Sensitivity in Cancer

Search Results for: flt3

Drugs (10)
Genetic Features (1)

Name	Synonyms	Targets	Target Pathway	PubCHEM	Datatset	Sample size	Screening site
Amuvatinib	MP470, MP 470, MP-470	KIT, PDGFRA, FLT3	RTK signaling	11282283	GDSC1	906	MGH
Cabozantinib	BMS-907351, XL-184, Cometriq	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, TIE2,AXL	RTK signaling	25102847	GDSC1	911	MGH
Cediranib	AZD2171, AZD 2171, AZD-2171, Recentin	VEGFR, FLT1, FLT2, FLT3, FLT4, KIT, PDGFRB	RTK signaling	9933475	GDSC2	958	SANGER
Lestaurtinib	CEP-701, SP-924, SPM-924, A-154475, KT-555	FLT3, JAK2, NTRK1, NTRK2, NTRK3	Other, kinases	126565	GDSC1	929	SANGER
Lestaurtinib	CEP-701, SP-924, SPM-924, A-154475, KT-555	FLT3, JAK2, NTRK1, NTRK2, NTRK3	Other, kinases	126565	GDSC2	947	SANGER
Linifanib	ABT-869, ABT 869	VEGFR1, VEGFR2, VEGFR3, CSF1R, FLT3, KIT	RTK signaling	11485656	GDSC1	914	MGH
Ponatinib	AP24534, AP-24534, KIN001-192, Iclusig	ABL, PDGFRA, VEGFR2, FGFR1, SRC, TIE2, FLT3	Other, kinases	24826799	GDSC1	877	MGH
Quizartinib	AC220, AC 220, AC-220, Asp-2689	FLT3	RTK signaling	24889392	GDSC1	914	MGH
Sunitinib	Sutent, Sunitinib Malate, SU-11248	PDGFR, KIT, VEGFR, FLT3, RET, CSF1R	RTK signaling	5329102	GDSC1	396	MGH
WZ3105		SRC, ROCK2, NTRK2, FLT3, IRAK1, others	Other	none	GDSC1	914	MGH

Feature Name	Feature Type
FLT3_mut	coding variant

The Genomics of Drug Sensitivity in Cancer Project is a collaboration between the Cancer Genome Project at the Wellcome Sanger Institute (UK) and the Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center (USA). This work is funded by Wellcome.

Users have a non-exclusive, non-transferable right to use data files for internal proprietary research and educational purposes, including target, biomarker and drug discovery. Excluded from this licence are use of the data (in whole or any significant part) for resale either alone or in combination with additional data/product offerings, or for provision of commercial services.
Please note: The data files are experimental and academic in nature and are not licensed or certified by any regulatory body. Genome Research Limited provides access to data files on an “as is” basis and excludes all warranties of any kind (express or implied).