Search results for : myc - Cancerrxgene - Genomics of Drug Sensitivity in Cancer

Search Results for: myc

Drugs (14)
Genetic Features (1)

Name	Synonyms	Targets	Target Pathway	PubCHEM	Datatset	Sample size	Screening site
Bleomycin		dsDNA break induction	DNA replication	several	GDSC1	856	MGH
Bleomycin		dsDNA break induction	DNA replication		GDSC2	717	SANGER
Bleomycin (10 uM)		dsDNA break induction	DNA replication		GDSC1	918	SANGER
Bleomycin (50 uM)		dsDNA break induction	DNA replication	5460769	GDSC1	921	SANGER
Bleomycin (50 uM)		dsDNA break induction	DNA replication	5460769	GDSC2	731	SANGER
Dactinomycin	Actinomycin D	RNA polymerase	Other		GDSC2	717	SANGER
Dactinomycin	Actinomycin D, Cosmegen, Lyovac, Meractinomycin, Ac-De, ActD	RNA polymerase	Other	several	GDSC2	942	SANGER
Doxorubicin	Doxil, Rubex, Adriamycin, Adriablastin, Doxorubicine	Anthracycline	DNA replication	31703	GDSC1	870	MGH
Mitomycin-C	Mytozytrex, NSC-26980, MMC, Mitosol, Mitozytrex	DNA crosslinker	DNA replication	5746	GDSC1	870	MGH
Mycophenolic acid			Unclassified		GDSC2	737	SANGER
Rapamycin	AY-22989, Sirolimus, WY-090217, Torisel, Rapamune	MTORC1	PI3K/MTOR signaling	5384616	GDSC1	357	MGH
Rapamycin	AY-22989, Sirolimus, WY-090217, Torisel, Rapamune	MTORC1	PI3K/MTOR signaling	5384616	GDSC2	950	SANGER
Tanespimycin	17-AAG, BMS-722782	HSP90	Protein stability and degradation	6505803	GDSC1	930	SANGER
Tanespimycin	17-AAG, BMS-722782	HSP90	Protein stability and degradation	6505803	GDSC2	949	SANGER

Feature Name	Feature Type
MYC_mut	coding variant

The Genomics of Drug Sensitivity in Cancer Project is a collaboration between the Cancer Genome Project at the Wellcome Sanger Institute (UK) and the Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center (USA). This work is funded by Wellcome.

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