Search results for : nes - Cancerrxgene - Genomics of Drug Sensitivity in Cancer

Search Results for: nes

Drugs (9)

Name	Synonyms	Targets	Target Pathway	PubCHEM	Datatset	Sample size	Screening site
BDOCA000347a	4-bromo-N-(6-methoxy-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methylbenzenesulfonamide	BRPF1, BRPF2, BRPF3	Chromatin histone acetylation		GDSC2	717	SANGER
Bromosporine	ethyl N-[6-(3-methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate	CECR2, BRD2, BRD4, BRD9	Chromatin other		GDSC2	716	SANGER
FTI-277		Farnesyl-transferase (FNTA)	Other	3005532	GDSC1	880	MGH
Ispinesib Mesylate	SB-715992	KSP	Mitosis	6450816	GDSC1	911	MGH
Luminespib	AUY922, VER-52296,NVP-AUY922, AUY	HSP90	Protein stability and degradation	10096043	GDSC1	862	MGH
Luminespib	AUY922, VER-52296,NVP-AUY922, AUY	HSP90	Protein stability and degradation	10096043	GDSC2	964	SANGER
Tanespimycin	17-AAG, BMS-722782	HSP90	Protein stability and degradation	6505803	GDSC1	930	SANGER
Tanespimycin	17-AAG, BMS-722782	HSP90	Protein stability and degradation	6505803	GDSC2	949	SANGER
Tipifarnib	Zarnestra	Farnesyl-transferase (FNTA)	Other	159324	GDSC1	871	MGH

The Genomics of Drug Sensitivity in Cancer Project is a collaboration between the Cancer Genome Project at the Wellcome Sanger Institute (UK) and the Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center (USA). This work is funded by Wellcome.

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