Search results for : ran - Cancerrxgene - Genomics of Drug Sensitivity in Cancer

Search Results for: ran

Drugs (15)
Celllines ( 2)

Name	Synonyms	Targets	Target Pathway	PubCHEM	Datatset	Sample size	Screening site
5-azacytidine		DNA methyltransferases	Other		GDSC2	740	SANGER
AICA Ribonucleotide	AICAR, N1-(b-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide	AMPK agonist	Metabolism	65110	GDSC1	925	SANGER
Ara-G	9-??-D-Arabinofuranosyl guanine	Anti-metabolite	Other		GDSC1	906	MGH
Cediranib	AZD2171, AZD 2171, AZD-2171, Recentin	VEGFR, FLT1, FLT2, FLT3, FLT4, KIT, PDGFRB	RTK signaling	9933475	GDSC2	958	SANGER
FTI-277		Farnesyl-transferase (FNTA)	Other	3005532	GDSC1	880	MGH
Fulvestrant	SN0117217688	ESR1	Hormone-related		GDSC1	915	SANGER
Fulvestrant	Faslodex, ICI-182780	ESR	Hormone-related	104741	GDSC2	963	SANGER
Fulvestrant		ESR	Hormone-related		GDSC2	717	SANGER
ICL1100013		N-myristoyltransferase 1/2	Other		GDSC1	901	SANGER
Nelarabine	Atriance, Arranon		DNA replication		GDSC2	716	SANGER
Tipifarnib	Zarnestra	Farnesyl-transferase (FNTA)	Other	159324	GDSC1	871	MGH
UNC0638	UNC-0638, UNC 0683	G9a and GLP methyltransferases	Chromatin histone methylation	46224516	GDSC1	907	MGH
UNC0638	UNC-0638, UNC 0683	G9a and GLP methyltransferases	Chromatin histone methylation	46224516	GDSC1	914	SANGER
Vorinostat	Zolinza, SAHA, suberanilohydroxamic acid, suberoylanilide hydroxamic acid, MK-0683	HDAC inhibitor Class I, IIa, IIb, IV	Chromatin histone acetylation	5311	GDSC1	933	SANGER
Vorinostat	Zolinza, SAHA, suberanilohydroxamic acid, suberoylanilide hydroxamic acid, MK-0683	HDAC inhibitor Class I, IIa, IIb, IV	Chromatin histone acetylation	5311	GDSC2	959	SANGER

Name	Cell Model Passport Link	COSMIC ID	Tissue	Tissue sub-type
GRANTA-519	SIDM01058	1303897	DLBC	Blood
GRANTA-519	SIDM01058	1303897	DLBC	Blood

The Genomics of Drug Sensitivity in Cancer Project is a collaboration between the Cancer Genome Project at the Wellcome Sanger Institute (UK) and the Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center (USA). This work is funded by Wellcome.

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