Home

A landscape of pharmacogenomic interaction in cancer:

Resources and Results

Home Data Summary Cancer Functional Events (CFEs) CFEs in Primary Tumours (PTs) CFEs in Cell Lines (CLs) Pathway Activity Scores in CLs PTs vs CLs Comparison

Restore row order

Pharmacogenomic interactions

Drug screening data

Logic models of drug response

Machine Learning analyses

Precision medicine landscape

This website and linked web pages contain data objects, results and supplementary data items related to and/or presented in the paper A landscape of pharmacogenomic interactions in cancer [Iorio et al, Cell 2016]. All the content is available in the table below and it also distributed across a set of web-pages (accessible through the below menu) roughly related to individual data-curation/analytical-aspects of the study.

The below table contains also tags indicating the data omic covered by the corresponding item or specifying if this is an annotation objects, as defined below:

SEQ: genomic variants, coded genomic variants, generally from whole exome sequencing (WES) profiles;

CNV: coded or plain information about copy number altered genes and chromosomal segments;

METH: coded or plain epigenomic data;

EXP: trascriptional data;

DR: raw or processed, drug response data and drug sensitivity indicators;

MULT: combination of different data types (for example, somatic mutations and copy number alterations for a sub set of samples);

ANN: annotation items (such as, sample name catalogues, studies, tissue classifications etc.);

The second column roughly indicates the amount of processing performed to generate the item in a given row. Tags in this column ranges from Raw (for raw data) to Analysis (for results of the study).

Distributed under the GPLv3 License.
See file LICENSE.txt at http://www.gnu.org/licenses/gpl-3.0.html

Credits