ANOVA BLCA result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-04-08 10:28:13 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: BLCA specific


Individual drug analysis: 1529


Drug details and screening numbers

Drug Name: MLN4924
Drug ID: 1529
Synonyms:
Brand name:
Target: NEDD8-activating enzyme

Number of cell lines screened: 703
Screening concentration range(s): 0.00390625 to 1 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a4

ARID1A_mut

1529

1

1

MLN4924

NEDD8-activating enzyme

3

13

0

-0.796

2.21

3.01

2.8 **

2.7 **

4.4 **

6.34e-04

NA

NA

24

All-tests volcano plot