ANOVA BRCA specific result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:18:57 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: BRCA specific


Individual drug analysis: 1218


Drug details and screening numbers

Drug Name: JQ1
Drug ID: 1218
Synonyms:
Brand name:
Target: BRD2, BRD3, BRD4

Number of cell lines screened: 915
Screening concentration range(s): 0.00390625 to 1 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a20

POLR2B_mut

1218

1

1

JQ1

BRD2, BRD3, BRD4

3

43

0

2.55

1.13

-1.42

2.3 **

2.3 **

3.9 **

3.39e-04

NA

NA

19

All-tests volcano plot