ANOVA BRCA specific result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:18:57 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: BRCA specific


Individual drug analysis: 224


Drug details and screening numbers

Drug Name: AS605240
Drug ID: 224
Synonyms: KIN001-173
Brand name:
Target: PI3Kgamma

Number of cell lines screened: 921
Screening concentration range(s): 0.078125 to 20 uM and 0.04 to 10.24 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a35

gain_cnaBRCA64_(SDHC)

224

1

1

AS605240

PI3Kgamma

8

41

3.00, 2.33

3.59

1.61

-1.98

1.4 *

1.8 *

0.78 .

6.64e-04

NA

NA

22

All-tests volcano plot