ANOVA LAML specific result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:30:59 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: LAML specific


Individual drug analysis: 238


Drug details and screening numbers

Drug Name: CAL-101
Drug ID: 238
Synonyms:
Brand name:
Target: PI3Kdelta

Number of cell lines screened: 925
Screening concentration range(s): 0.078125 to 20 uM and 0.04 to 10.24 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a16

NRAS_mut

238

1

1

CAL-101

PI3Kdelta

7

19

3.00, 2.33

2.09

3.99

1.9

1.9 *

2 *

1.7 *

4.51e-04

NA

5.21e-02

3.3

All-tests volcano plot