ANOVA LAML specific result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:30:59 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: LAML specific


Individual drug analysis: 290


Drug details and screening numbers

Drug Name: KIN001-260
Drug ID: 290
Synonyms: Bayer IKKb inhibitor
Brand name:
Target: IKK

Number of cell lines screened: 921
Screening concentration range(s): 0.078125 to 20 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a4

NRAS_mut

290

1

1

KIN001-260

IKK

7

18

3

2.33

3.96

1.64

2.1 **

2.3 **

1.8 *

1.37e-04

NA

8.03e-02

2.9

All-tests volcano plot