ANOVA LAML specific result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:30:59 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: LAML specific


Individual drug analysis: 299


Drug details and screening numbers

Drug Name: OSI-027
Drug ID: 299
Synonyms: activebiochem A-1065
Brand name:
Target: MTORC1/2

Number of cell lines screened: 918
Screening concentration range(s): 0.078125 to 20 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a17

NRAS_mut

299

1

1

OSI-027

MTORC1/2

7

19

3

-1.88

0.296

2.17

1.6 *

1.9 *

1.2 *

4.61e-04

NA

1.06e-04

3.3

All-tests volcano plot