ANOVA LAML specific result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:30:59 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: LAML specific


Individual drug analysis: 35


Drug details and screening numbers

Drug Name: NVP-TAE684
Drug ID: 35
Synonyms: KIN001-017
Brand name: TAE684
Target: ALK

Number of cell lines screened: 408
Screening concentration range(s): 0.0078125 to 2 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a18

NRAS_mut

35

1

1

NVP-TAE684

ALK

7

19

0.693

-0.537

1.46

1.99

1.9 *

1.9 *

1.8 *

5.48e-04

NA

2.5e-01

3.3

All-tests volcano plot