ANOVA OV specific result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:38:53 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: OV specific


Individual drug analysis: 1149


Drug details and screening numbers

Drug Name: TW 37
Drug ID: 1149
Synonyms:
Brand name:
Target: BCL2, BCL2L1

Number of cell lines screened: 920
Screening concentration range(s): 0.01953125 to 5 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a2

loss_cnaOV102

1149

1

1

TW 37

BCL2, BCL2L1

3

30

1.61

-0.942

1.28

2.22

3.4 **

3.3 **

9.6 **

4.72e-06

NA

5.24e-03

2.1

All-tests volcano plot