ANOVA OV specific result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:38:53 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: OV specific


Individual drug analysis: 326


Drug details and screening numbers

Drug Name: GSK690693
Drug ID: 326
Synonyms:
Brand name:
Target: AKT

Number of cell lines screened: 922
Screening concentration range(s): 0.04 to 10.24 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a3

PIK3CA_mut

326

1

1

GSK690693

AKT

6

26

2.33

4.65

1.97

-2.68

2.7 **

3.4 **

1.6 *

6.73e-06

NA

2.02e-02

2.1

All-tests volcano plot