ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:13
iorio@ebi.ac.uk


Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1008


Drug details and screening numbers

Drug Name: Methotrexate
Drug ID: 1008
Synonyms:
Brand name: Methotrexate
Target: Dihydrofolate reductase (DHFR)

Number of cell lines screened: 849
Screening concentration range(s): 0.00078125 to 0.2 uM


Statistically significant associations identified = 2
association id
FEATURE
Drug id
Propr
Public
Drug Name
Drug Target
N FEATURE pos
N FEATURE neg
log max Conc tested
FEATURE neg logIC50 MEAN
FEATURE pos logIC50 MEAN
FEATURE deltaMEAN IC50
FEATURE IC50 effectSize
FEATURE neg Glass delta
FEATURE pos Glass delta
ANOVA FEATURE pval
Tissue ANOVA pval
MSI ANOVA pval
ANOVA FEATURE FDR %
a423
loss_cnaPANCAN26
1008
1
1
Methotrexate
Dihydrofolate reductase (DHFR)
238
608
-1.61
-0.717
-0.0957
0.621
0.36
0.34
0.42
5.18e-04
5.53e-84
4.38e-02
20
a504
loss_cnaPANCAN361
1008
1
1
Methotrexate
Dihydrofolate reductase (DHFR)
43
803
-1.61
-0.571
0.00844
0.58
0.33
0.33
0.36
7.36e-04
6.35e-84
4.38e-02
24


All-tests volcano plot