ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 1010
Drug details and screening numbers
Drug Name: Gefitinib
Drug ID: 1010
Synonyms: ZD-1839
Brand name: Iressa
Target: EGFR
Number of cell lines screened: 846
Screening concentration range(s): 0.001953125 to 0.5 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a218 |
gain_cnaPANCAN124_(EGFR) |
1010 |
1 |
1 |
Gefitinib |
EGFR |
88 |
755 |
-0.693 |
1.1 |
0.613 |
-0.487 |
0.44 |
0.48 |
0.29 |
1.05e-04 |
9.17e-26 |
8.36e-02 |
7.9 |
a362 |
EGFR_mut |
1010 |
1 |
1 |
Gefitinib |
EGFR |
21 |
822 |
-0.693 |
1.07 |
0.213 |
-0.858 |
0.78 . |
0.8 . |
0.45 |
3.65e-04 |
1.13e-25 |
8.4e-02 |
17 |
a443 |
HLA-A_mut |
1010 |
1 |
1 |
Gefitinib |
EGFR |
13 |
830 |
-0.693 |
1.07 |
-0.36 |
-1.43 |
1.3 * |
1.3 * |
0.87 . |
5.63e-04 |
1.21e-25 |
8.42e-02 |
21 |
All-tests volcano plot
