ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 1016
Drug details and screening numbers
Drug Name: Temsirolimus
Drug ID: 1016
Synonyms: CCI-779
Brand name: Torisel
Target: MTOR
Number of cell lines screened: 837
Screening concentration range(s): 0.00078125 to 0.2 uM
Statistically significant associations identified = 2
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a302 |
PGR_mut |
1016 |
1 |
1 |
Temsirolimus |
MTOR |
3 |
832 |
-1.61 |
-2.03 |
-5.17 |
-3.14 |
1.9 * |
1.9 * |
0.93 . |
2.45e-04 |
1.29e-21 |
1.53e-01 |
13 |
a381 |
gain_cnaPANCAN1_(CCNE1) |
1016 |
1 |
1 |
Temsirolimus |
MTOR |
37 |
798 |
-1.61 |
-2.09 |
-1.13 |
0.957 |
0.59 . |
0.59 . |
0.75 . |
3.97e-04 |
1.39e-21 |
1.53e-01 |
17 |
All-tests volcano plot
