ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:12 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1026


Drug details and screening numbers

Drug Name: 17-AAG
Drug ID: 1026
Synonyms: 17-AAG
Brand name: Telatinib
Target: HSP90

Number of cell lines screened: 850
Screening concentration range(s): 0.00390625 to 1 uM


Statistically significant associations identified = 3

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a394	loss_cnaPANCAN250_(SRGAP3)	1026	1	1	17-AAG	HSP90	144	703	0	-0.626	-0.149	0.477	0.26	0.26	0.26	4.44e-04	2.68e-39	4.15e-01	19
a404	loss_cnaPANCAN251, loss_cnaPANCAN252	1026	1	1	17-AAG	HSP90	65	782	0	-0.597	0.0855	0.683	0.38	0.38	0.37	4.78e-04	2.73e-39	4.15e-01	20
a439	loss_cnaPANCAN253	1026	1	1	17-AAG	HSP90	69	778	0	-0.6	0.0816	0.682	0.38	0.38	0.36	5.44e-04	2.81e-39	4.16e-01	20

All-tests volcano plot