ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1031


Drug details and screening numbers

Drug Name: Elesclomol
Drug ID: 1031
Synonyms:
Brand name:
Target: HSP70

Number of cell lines screened: 849
Screening concentration range(s): 0.00078125 to 0.2 uM


Statistically significant associations identified = 2

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a355

SMARCA4_mut

1031

1

1

Elesclomol

HSP70

41

805

-1.61

-2.98

-3.7

-0.72

0.4

0.4

0.52 .

3.59e-04

1.01e-15

4.82e-01

17

a402

gain_cnaPANCAN382_(FLT3,WASF3)

1031

1

1

Elesclomol

HSP70

16

830

-1.61

-3.05

-0.994

2.06

1.2 *

1.2 *

1 *

4.72e-04

1.04e-15

4.82e-01

19

All-tests volcano plot