ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:14 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1037


Drug details and screening numbers

Drug Name: BX-795
Drug ID: 1037
Synonyms: BX 795
Brand name:
Target: TBK1, PDPK1, IKK, AURKB, AURKC

Number of cell lines screened: 849
Screening concentration range(s): 0.01953125 to 5 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a517

loss_cnaPANCAN320

1037

1

1

BX-795

TBK1, PDPK1, IKK, AURKB, AURKC

11

835

1.61

1.87

3.07

1.2

0.95 .

0.96 .

0.7 .

7.7e-04

1.6e-19

5.11e-01

25

All-tests volcano plot