ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1066


Drug details and screening numbers

Drug Name: AZD6482
Drug ID: 1066
Synonyms: WO2009093972
Brand name:
Target: PI3Kbeta

Number of cell lines screened: 900
Screening concentration range(s): 0.01953125 to 5 uM


Statistically significant associations identified = 2

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a237	loss_cnaPANCAN257	1066	1	1	AZD6482	PI3Kbeta	281	616	1.61	2.18	2.58	0.402	0.31	0.31	0.31	1.27e-04	7.34e-19	6.99e-02	8.9
a516	loss_cnaPANCAN262_(FOXP1)	1066	1	1	AZD6482	PI3Kbeta	82	815	1.61	2.27	2.7	0.438	0.34	0.34	0.35	7.69e-04	9.16e-19	7.04e-02	25

All-tests volcano plot