ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:12 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1091


Drug details and screening numbers

Drug Name: BMS-536924
Drug ID: 1091
Synonyms: BMS-536924
Brand name:
Target: IGF1R

Number of cell lines screened: 926
Screening concentration range(s): 0.015625 to 4 uM


Statistically significant associations identified = 2

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a409	gain_cnaPANCAN213_(MCM3)	1091	1	1	BMS-536924	IGF1R	52	871	1.39	2.15	2.68	0.531	0.45	0.45	0.51 .	4.9e-04	1.41e-12	6.35e-01	20
a415	gain_cnaPANCAN301_(CDK12,ERBB2,MED24)	1091	1	1	BMS-536924	IGF1R	49	874	1.39	2.14	2.92	0.784	0.68 .	0.67 .	0.69 .	5.05e-04	1.41e-12	6.35e-01	20

All-tests volcano plot