ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 1243
Drug details and screening numbers
Drug Name: piperlongumine
Drug ID: 1243
Synonyms:
Brand name:
Target: Increases ROS levels
Number of cell lines screened: 928
Screening concentration range(s): 0.0390625 to 10 uM
Statistically significant associations identified = 2
association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a252 |
loss_cnaPANCAN138 |
1243 |
1 |
1 |
piperlongumine |
Increases ROS levels |
20 |
905 |
2.3 |
1.65 |
2.49 |
0.834 |
0.88 . |
0.88 . |
0.69 . |
1.57e-04 |
7.02e-15 |
2.93e-02 |
10 |
a331 |
SVEP1_mut |
1243 |
1 |
1 |
piperlongumine |
Increases ROS levels |
11 |
914 |
2.3 |
1.66 |
2.63 |
0.976 |
1 * |
1 * |
0.75 . |
3e-04 |
7.49e-15 |
2.94e-02 |
15 |
All-tests volcano plot