ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 230


Drug details and screening numbers

Drug Name: GSK429286A
Drug ID: 230
Synonyms:
Brand name:
Target: ROCK2

Number of cell lines screened: 926
Screening concentration range(s): 0.078125 to 20 uM and 0.04 to 10.24 uM


Statistically significant associations identified = 5

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a210	loss_cnaPANCAN15	230	1	1	GSK429286A	ROCK2	22	901	3.00, 2.33	4.77	3.91	-0.862	0.73 .	0.73 .	0.6 .	9.37e-05	2.3e-54	9.07e-01	7.4
a221	loss_cnaPANCAN13	230	1	1	GSK429286A	ROCK2	20	903	3.00, 2.33	4.77	3.9	-0.867	0.73 .	0.74 .	0.56 .	1.14e-04	2.43e-54	9.07e-01	8.5
a264	loss_cnaPANCAN14	230	1	1	GSK429286A	ROCK2	22	901	3.00, 2.33	4.77	3.94	-0.829	0.7 .	0.71 .	0.56 .	1.75e-04	2.72e-54	9.07e-01	11
a332	loss_cnaPANCAN16	230	1	1	GSK429286A	ROCK2	15	908	3.00, 2.33	4.77	3.69	-1.08	0.91 .	0.91 .	0.76 .	3.01e-04	3.15e-54	9.07e-01	15
a464	IDH1_mut	230	1	1	GSK429286A	ROCK2	4	919	3.00, 2.33	4.76	3.05	-1.71	1.4 *	1.4 *	1 *	6.02e-04	3.8e-54	9.07e-01	21

All-tests volcano plot