ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 231
Drug details and screening numbers
Drug Name: FMK
Drug ID: 231
Synonyms: KIN001-242
Brand name:
Target: RSK
Number of cell lines screened: 795
Screening concentration range(s): 0.078125 to 20 uM and 0.04 to 10.24 uM
Statistically significant associations identified = 2
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a229 |
C15orf55_mut |
231 |
1 |
1 |
FMK |
RSK |
3 |
789 |
3.00, 2.33 |
5.02 |
3.68 |
-1.34 |
1.6 * |
1.6 * |
0.72 . |
1.23e-04 |
1.7e-40 |
4.77e-01 |
8.8 |
a256 |
loss_cnaPANCAN167 |
231 |
1 |
1 |
FMK |
RSK |
15 |
777 |
3.00, 2.33 |
5 |
5.6 |
0.594 |
0.72 . |
0.72 . |
0.65 . |
1.6e-04 |
1.81e-40 |
4.77e-01 |
10 |
All-tests volcano plot
