ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 89
Drug details and screening numbers
Drug Name: Parthenolide
Drug ID: 89
Synonyms:
Brand name:
Target: NFKB1
Number of cell lines screened: 403
Screening concentration range(s): 0.01953125 to 5 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a271 |
MLL_mut |
89 |
1 |
1 |
Parthenolide |
NFKB1 |
13 |
389 |
1.61 |
2.99 |
2.11 |
-0.885 |
0.73 . |
0.73 . |
0.64 . |
1.82e-04 |
2.18e-07 |
8.94e-01 |
11 |
a396 |
RB1_mut |
89 |
1 |
1 |
Parthenolide |
NFKB1 |
53 |
349 |
1.61 |
2.96 |
2.97 |
0.00811 |
0.0066 |
0.0067 |
0.0065 |
4.45e-04 |
2.45e-07 |
8.94e-01 |
19 |
a506 |
NR4A2_mut |
89 |
1 |
1 |
Parthenolide |
NFKB1 |
3 |
399 |
1.61 |
2.98 |
0.906 |
-2.07 |
1.7 * |
1.7 * |
2.8 ** |
7.38e-04 |
2.61e-07 |
8.95e-01 |
24 |
All-tests volcano plot
