| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE pos logIC50 MEAN |
FEATURE neg logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
ANOVA Tissue pval |
ANOVA MSI pval |
ANOVA FEATURE %FDR |
a1 |
loss_cnaBLCA18_(CHD9,CNOT1,CYLD,MMP2,NUP93) |
1230 |
|
1 |
IOX2 |
EGLN1 |
3 |
16 |
-2.3 |
-1.37 |
0.0769 |
-1.44 |
3.3 ** |
5.2 ** |
1.4 * |
6.67e-05 |
NA |
NA |
11 |
a2 |
TP53_mut |
136 |
|
1 |
Mitomycin C |
DNA crosslinker |
15 |
4 |
2.77 |
-1.84 |
1.11 |
-2.94 |
2.8 ** |
4.1 ** |
2.7 ** |
9.94e-05 |
NA |
NA |
11 |
a3 |
gain_cnaBLCA15_(ASXL1) |
269 |
|
1 |
NSC-207895 |
MDM4 |
6 |
13 |
3 |
5.01 |
2.96 |
2.05 |
2.4 ** |
3 ** |
1.7 * |
1.7e-04 |
NA |
NA |
12 |
a4 |
ARID1A_mut |
1529 |
|
1 |
MLN4924 |
NEDD8-activating enzyme |
3 |
13 |
0 |
2.21 |
-0.796 |
3.01 |
2.8 ** |
2.7 ** |
4.4 ** |
6.34e-04 |
NA |
NA |
24 |
a5 |
TP53_mut |
133 |
|
1 |
Doxorubicin |
DNA intercalating |
15 |
4 |
0.0237 |
-2.69 |
0.221 |
-2.91 |
2.3 ** |
2 ** |
2.4 ** |
7.13e-04 |
NA |
NA |
24 |
a6 |
TP53_mut |
135 |
|
1 |
Gemcitabine |
DNA replication |
15 |
4 |
0.0237 |
-3.36 |
1.46 |
-4.82 |
2.3 ** |
3.5 ** |
2.2 ** |
7.27e-04 |
NA |
NA |
24 |
a7 |
ARID1A_mut |
305 |
|
1 |
TPCA-1 |
IKK |
5 |
14 |
3 |
5.31 |
2.94 |
2.37 |
2.1 ** |
1.9 * |
3.2 ** |
8.72e-04 |
NA |
NA |
24 |
a8 |
ARID1A_mut |
228 |
|
1 |
KIN001-102 |
AKT1 |
5 |
14 |
2.33 |
4.8 |
2.83 |
1.97 |
2.1 ** |
1.9 * |
3.2 ** |
9.29e-04 |
NA |
NA |
24 |
