ANOVA BRCA specific result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:18:57 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: BRCA specific


Individual drug analysis: 1375


Drug details and screening numbers

Drug Name: Temozolomide
Drug ID: 1375
Synonyms: Temodar
Brand name:
Target: DNA akylating agent

Number of cell lines screened: 910
Screening concentration range(s): 0.1171875 to 30 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a28

gain_cnaBRCA30_(CRNKL1,FOXA2)

1375

1

1

Temozolomide

DNA akylating agent

5

41

3.4

5.78

6.87

1.09

1.8 *

1.8 *

1.5 *

4.74e-04

NA

NA

19

All-tests volcano plot