ANOVA BRCA specific result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:18:57 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: BRCA specific


Individual drug analysis: 140


Drug details and screening numbers

Drug Name: Vinorelbine
Drug ID: 140
Synonyms:
Brand name: Navelbine
Target: Microtubules

Number of cell lines screened: 885
Screening concentration range(s): 0.00025 to 0.064 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a26

gain_cnaBRCA30_(CRNKL1,FOXA2)

140

1

1

Vinorelbine

Microtubules

5

42

-2.75

-3.88

-1.28

2.59

1.8 *

1.8 *

2 *

4.38e-04

NA

NA

19

All-tests volcano plot