ANOVA COREAD specific result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:22:41 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: COREAD specific
Individual drug analysis: 326
Drug details and screening numbers
Drug Name: GSK690693
Drug ID: 326
Synonyms:
Brand name:
Target: AKT
Number of cell lines screened: 922
Screening concentration range(s): 0.04 to 10.24 uM
Statistically significant associations identified = 4
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a5 |
PTEN_mut |
326 |
1 |
1 |
GSK690693 |
AKT |
6 |
40 |
2.33 |
4.44 |
1.81 |
-2.63 |
2.4 ** |
2.5 ** |
1.8 * |
3.49e-06 |
NA |
2.31e-01 |
1.3 |
a9 |
MAP2K4_mut |
326 |
1 |
1 |
GSK690693 |
AKT |
5 |
41 |
2.33 |
4.39 |
1.75 |
-2.64 |
2.3 ** |
2.4 ** |
1.6 * |
1.89e-05 |
NA |
2.48e-01 |
3.9 |
a21 |
CNOT1_mut |
326 |
1 |
1 |
GSK690693 |
AKT |
3 |
43 |
2.33 |
4.29 |
1.32 |
-2.98 |
2.5 ** |
2.6 ** |
1.6 * |
1.51e-04 |
NA |
2.7e-01 |
13 |
a22 |
ARID2_mut |
326 |
1 |
1 |
GSK690693 |
AKT |
7 |
39 |
2.33 |
4.42 |
2.32 |
-2.1 |
1.8 * |
2 * |
1.2 * |
1.77e-04 |
NA |
2.71e-01 |
15 |
All-tests volcano plot
