ANOVA LAML specific result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 12:30:59 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: LAML specific


Individual drug analysis: 179


Drug details and screening numbers

Drug Name: 5-Fluorouracil
Drug ID: 179
Synonyms: 5-Fluorouracil
Brand name:
Target: DNA antimetabolite

Number of cell lines screened: 916
Screening concentration range(s): 0.125 to 32 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a26

TP53_mut

179

1

1

5-Fluorouracil

DNA antimetabolite

12

13

3.47

0.461

2.33

1.87

1.4 *

1.7 *

1.2 *

8.35e-04

NA

1.98e-02

3.9

All-tests volcano plot