| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE pos logIC50 MEAN |
FEATURE neg logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
ANOVA Tissue pval |
ANOVA MSI pval |
ANOVA FEATURE %FDR |
a1 |
loss_cnaOV102 |
1012 |
|
1 |
Vorinostat |
HDAC inhibitor Class I, IIa, IIb, IV |
3 |
28 |
2.3 |
4.81 |
1.04 |
3.76 |
4 ** |
4.1 ** |
3.7 ** |
5.38e-07 |
NA |
2.68e-01 |
0.51 |
a2 |
loss_cnaOV102 |
1149 |
|
1 |
TW 37 |
BCL2, BCL2L1 |
3 |
30 |
1.61 |
1.28 |
-0.942 |
2.22 |
3.4 ** |
3.3 ** |
9.6 ** |
4.72e-06 |
NA |
5.24e-03 |
2.1 |
a3 |
PIK3CA_mut |
326 |
|
1 |
GSK690693 |
AKT |
6 |
26 |
2.33 |
1.97 |
4.65 |
-2.68 |
2.7 ** |
3.4 ** |
1.6 * |
6.73e-06 |
NA |
2.02e-02 |
2.1 |
a4 |
TP53_mut |
1047 |
|
1 |
Nutlin-3a |
MDM2 |
23 |
10 |
2.08, 1.39 |
4.39 |
2.27 |
2.12 |
1.8 * |
1.5 * |
1.9 * |
1.31e-05 |
NA |
6.05e-02 |
3.1 |
a5 |
loss_cnaOV43_(NF1) |
1012 |
|
1 |
Vorinostat |
HDAC inhibitor Class I, IIa, IIb, IV |
5 |
26 |
2.3 |
3.71 |
0.966 |
2.75 |
2.6 ** |
3 ** |
1.6 * |
1.68e-05 |
NA |
3.24e-01 |
3.2 |
