ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1001


Drug details and screening numbers

Drug Name: AICAR
Drug ID: 1001
Synonyms: N1-(b-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide
Brand name: AICAR
Target: AAPK1 (AMPK) agonist

Number of cell lines screened: 840
Screening concentration range(s): 7.8125 to 2000 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a292

gain_cnaPANCAN273

1001

1

1

AICAR

AAPK1 (AMPK) agonist

33

804

7.6

7.77

8.52

0.743

0.57 .

0.57 .

0.49

2.18e-04

4.47e-40

4.61e-01

12

All-tests volcano plot