ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:02:15 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual Feature analysis: gain_cnaPANCAN273
Feature details and cell panel numbers
Binary feature equal to 1 for samples having the genomic region(s) cnaPANCAN273 amplified (see genomic region decoding file for further infos on this region)
Number of cell lines positive for this feature: 39
Statistically significant associations identified = 2
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a292 |
gain_cnaPANCAN273 |
1001 |
1 |
1 |
AICAR |
AAPK1 (AMPK) agonist |
33 |
804 |
7.6 |
7.77 |
8.52 |
0.743 |
0.57 . |
0.57 . |
0.49 |
2.18e-04 |
4.47e-40 |
4.61e-01 |
12 |
a519 |
gain_cnaPANCAN273 |
1054 |
1 |
1 |
PD-0332991 |
CDK4, CDK6 |
34 |
789 |
1.386, 0.693 |
1.73 |
2.8 |
1.07 |
0.67 . |
0.67 . |
0.67 . |
7.75e-04 |
3.8e-27 |
1.91e-02 |
25 |
All-tests volcano plot
