| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a31 |
RB1_mut |
1054 |
1 |
1 |
PD-0332991 |
CDK4, CDK6 |
73 |
750 |
1.386, 0.693 |
1.63 |
3.27 |
1.64 |
1.1 * |
1 * |
1.3 * |
1.21e-08 |
5.03e-28 |
1.75e-02 |
0.0064 |
a96 |
loss_cnaPANCAN144_(BNC2,CDKN2A,JAK2,PSIP1) |
1054 |
1 |
1 |
PD-0332991 |
CDK4, CDK6 |
473 |
350 |
1.386, 0.693 |
2.17 |
1.48 |
-0.687 |
0.44 |
0.42 |
0.45 |
8.75e-06 |
1.7e-27 |
1.84e-02 |
1.5 |
a172 |
gain_cnaPANCAN275_(SDHC) |
1054 |
1 |
1 |
PD-0332991 |
CDK4, CDK6 |
43 |
780 |
1.386, 0.693 |
1.71 |
2.96 |
1.25 |
0.79 . |
0.79 . |
0.78 . |
5.67e-05 |
2.39e-27 |
1.87e-02 |
5.4 |
a173 |
loss_cnaPANCAN389_(RB1) |
1054 |
1 |
1 |
PD-0332991 |
CDK4, CDK6 |
94 |
729 |
1.386, 0.693 |
1.66 |
2.65 |
0.993 |
0.63 . |
0.62 . |
0.7 . |
5.87e-05 |
2.4e-27 |
1.87e-02 |
5.6 |
a349 |
gain_cnaPANCAN270_(JUN) |
1054 |
1 |
1 |
PD-0332991 |
CDK4, CDK6 |
16 |
807 |
1.386, 0.693 |
1.75 |
3.1 |
1.36 |
0.85 . |
0.84 . |
0.97 . |
3.5e-04 |
3.31e-27 |
1.9e-02 |
16 |
a391 |
gain_cnaPANCAN280_(ARID4B,FH) |
1054 |
1 |
1 |
PD-0332991 |
CDK4, CDK6 |
50 |
773 |
1.386, 0.693 |
1.71 |
2.68 |
0.963 |
0.6 . |
0.61 . |
0.54 . |
4.34e-04 |
3.44e-27 |
1.9e-02 |
18 |
a519 |
gain_cnaPANCAN273 |
1054 |
1 |
1 |
PD-0332991 |
CDK4, CDK6 |
34 |
789 |
1.386, 0.693 |
1.73 |
2.8 |
1.07 |
0.67 . |
0.67 . |
0.67 . |
7.75e-04 |
3.8e-27 |
1.91e-02 |
25 |
