ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10
iorio@ebi.ac.uk


Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1004


Drug details and screening numbers

Drug Name: Vinblastine
Drug ID: 1004
Synonyms: Vinblastine sulphate
Brand name: Vinblastine
Target: Microtubules

Number of cell lines screened: 850
Screening concentration range(s): 0.000390625 to 0.1 uM


Statistically significant associations identified = 3
association id
FEATURE
Drug id
Propr
Public
Drug Name
Drug Target
N FEATURE pos
N FEATURE neg
log max Conc tested
FEATURE neg logIC50 MEAN
FEATURE pos logIC50 MEAN
FEATURE deltaMEAN IC50
FEATURE IC50 effectSize
FEATURE neg Glass delta
FEATURE pos Glass delta
ANOVA FEATURE pval
Tissue ANOVA pval
MSI ANOVA pval
ANOVA FEATURE FDR %
a231
gain_cnaPANCAN280_(ARID4B,FH)
1004
1
1
Vinblastine
Microtubules
52
795
-2.3
-4.1
-3.26
0.837
0.56 .
0.57 .
0.49
1.23e-04
7.06e-17
2.79e-02
8.8
a233
gain_cnaPANCAN411_(BLM,CRTC3,FANCI,IDH2,NR2F2,PCSK6)
1004
1
1
Vinblastine
Microtubules
22
825
-2.3
-4.08
-2.75
1.33
0.89 .
0.9 .
0.67 .
1.25e-04
7.07e-17
2.79e-02
8.8
a293
MYC_mut
1004
1
1
Vinblastine
Microtubules
5
842
-2.3
-4.05
-2.59
1.46
0.98 .
0.98 .
0.58 .
2.2e-04
7.56e-17
2.81e-02
12


All-tests volcano plot