ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1007


Drug details and screening numbers

Drug Name: Docetaxel
Drug ID: 1007
Synonyms: RP-56976
Brand name: Taxotere
Target: Microtubules

Number of cell lines screened: 850
Screening concentration range(s): 4.8828125e-05 to 0.0125 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a208

gain_cnaPANCAN280_(ARID4B,FH)

1007

1

1

Docetaxel

Microtubules

52

795

-4.38

-4.94

-4.25

0.686

0.46

0.46

0.42

9.19e-05

3.1e-31

2.57e-01

7.3

All-tests volcano plot