ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:09
iorio@ebi.ac.uk


Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1011


Drug details and screening numbers

Drug Name: ABT-263
Drug ID: 1011
Synonyms:
Brand name:
Target: BCL2, BCL2L1, BCL2L2

Number of cell lines screened: 849
Screening concentration range(s): 0.0078125 to 2 uM


Statistically significant associations identified = 3
association id
FEATURE
Drug id
Propr
Public
Drug Name
Drug Target
N FEATURE pos
N FEATURE neg
log max Conc tested
FEATURE neg logIC50 MEAN
FEATURE pos logIC50 MEAN
FEATURE deltaMEAN IC50
FEATURE IC50 effectSize
FEATURE neg Glass delta
FEATURE pos Glass delta
ANOVA FEATURE pval
Tissue ANOVA pval
MSI ANOVA pval
ANOVA FEATURE FDR %
a156
loss_cnaPANCAN286
1011
1
1
ABT-263
BCL2, BCL2L1, BCL2L2
34
812
0.693
1.28
0.125
-1.16
0.61 .
0.61 .
0.55 .
4.55e-05
6.99e-56
8.38e-03
4.8
a284
gain_cnaPANCAN272_(PIP5K1A,SETDB1)
1011
1
1
ABT-263
BCL2, BCL2L1, BCL2L2
50
796
0.693
1.19
2
0.817
0.43
0.43
0.45
2.08e-04
1.1e-55
8.49e-03
12
a366
gain_cnaPANCAN280_(ARID4B,FH)
1011
1
1
ABT-263
BCL2, BCL2L1, BCL2L2
51
795
0.693
1.17
2.25
1.08
0.57 .
0.57 .
0.67 .
3.71e-04
1.3e-55
8.54e-03
17


All-tests volcano plot