ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 1033
Drug details and screening numbers
Drug Name: Vismodegib
Drug ID: 1033
Synonyms: GDC-0449
Brand name: Erivedge
Target: SMO
Number of cell lines screened: 850
Screening concentration range(s): 0.0390625 to 10 uM
Statistically significant associations identified = 2
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a226 |
gain_cnaPANCAN91_(MYC) |
1033 |
1 |
1 |
Vismodegib |
SMO |
157 |
690 |
2.3 |
4.4 |
4.32 |
-0.0863 |
0.099 |
0.1 |
0.095 |
1.19e-04 |
1.64e-25 |
4.44e-01 |
8.7 |
a383 |
loss_cnaPANCAN234 |
1033 |
1 |
1 |
Vismodegib |
SMO |
42 |
805 |
2.3 |
4.36 |
4.89 |
0.532 |
0.61 . |
0.61 . |
0.62 . |
4.05e-04 |
2.01e-25 |
4.45e-01 |
17 |
All-tests volcano plot
