ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:12 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1039


Drug details and screening numbers

Drug Name: SL 0101-1
Drug ID: 1039
Synonyms:
Brand name:
Target: RSK, AURKB, PIM3

Number of cell lines screened: 834
Screening concentration range(s): 0.0390625 to 10 uM


Statistically significant associations identified = 2

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a401	loss_cnaPANCAN227, loss_cnaPANCAN228	1039	1	1	SL 0101-1	RSK, AURKB, PIM3	23	808	2.3	4.48	5.17	0.688	0.93 .	0.92 .	1.1 *	4.66e-04	1.81e-11	1.83e-01	19
a438	loss_cnaPANCAN229	1039	1	1	SL 0101-1	RSK, AURKB, PIM3	24	807	2.3	4.48	5.15	0.67	0.9 .	0.9 .	1.1 *	5.42e-04	1.83e-11	1.83e-01	20

All-tests volcano plot