ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1046


Drug details and screening numbers

Drug Name: 681640
Drug ID: 1046
Synonyms: 681640
Brand name:
Target: WEE1, CHEK1

Number of cell lines screened: 759
Screening concentration range(s): 0.0078125 to 2 uM


Statistically significant associations identified = 2

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a346	gain_cnaPANCAN301_(CDK12,ERBB2,MED24)	1046	1	1	681640	WEE1, CHEK1	41	716	0.693	2.07	2.78	0.708	0.65 .	0.65 .	0.71 .	3.41e-04	1.82e-08	4.09e-04	16
a475	gain_cnaPANCAN300	1046	1	1	681640	WEE1, CHEK1	24	733	0.693	2.09	2.94	0.854	0.78 .	0.78 .	0.82 .	6.46e-04	1.91e-08	4.13e-04	22

All-tests volcano plot