ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1149


Drug details and screening numbers

Drug Name: TW 37
Drug ID: 1149
Synonyms:
Brand name:
Target: BCL2, BCL2L1

Number of cell lines screened: 920
Screening concentration range(s): 0.01953125 to 5 uM


Statistically significant associations identified = 4

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a279	loss_cnaPANCAN162	1149	1	1	TW 37	BCL2, BCL2L1	23	894	1.61	-0.551	0.0822	0.634	0.54 .	0.54 .	0.41	2.01e-04	7.18e-16	5.77e-05	12
a419	loss_cnaPANCAN359_(CUL3)	1149	1	1	TW 37	BCL2, BCL2L1	19	898	1.61	-0.552	0.25	0.803	0.68 .	0.68 .	0.63 .	5.14e-04	7.93e-16	5.87e-05	20
a425	ANK3_mut	1149	1	1	TW 37	BCL2, BCL2L1	23	894	1.61	-0.553	0.14	0.693	0.59 .	0.59 .	0.55 .	5.18e-04	7.93e-16	5.87e-05	20
a484	loss_cnaPANCAN45	1149	1	1	TW 37	BCL2, BCL2L1	37	880	1.61	-0.564	0.131	0.695	0.59 .	0.59 .	0.54 .	6.7e-04	8.15e-16	5.9e-05	23

All-tests volcano plot