ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:09 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 1236
Drug details and screening numbers
Drug Name: UNC0638
Drug ID: 1236
Synonyms:
Brand name:
Target: G9a(EHMT2), GLP(EHMT1)
Number of cell lines screened: 931
Screening concentration range(s): 0.078125 to 20 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a142 |
SOS1_mut |
1236 |
1 |
1 |
UNC0638 |
G9a(EHMT2), GLP(EHMT1) |
9 |
919 |
3 |
3.22 |
2.15 |
-1.08 |
0.77 . |
0.78 . |
0.46 |
3.39e-05 |
1.35e-41 |
4.25e-01 |
3.9 |
a387 |
loss_cnaPANCAN215 |
1236 |
1 |
1 |
UNC0638 |
G9a(EHMT2), GLP(EHMT1) |
45 |
883 |
3 |
3.18 |
3.91 |
0.726 |
0.52 . |
0.52 . |
0.51 . |
4.24e-04 |
2.36e-41 |
4.27e-01 |
18 |
a527 |
BRAF_mut |
1236 |
1 |
1 |
UNC0638 |
G9a(EHMT2), GLP(EHMT1) |
82 |
846 |
3 |
3.25 |
2.81 |
-0.444 |
0.32 |
0.32 |
0.37 |
7.93e-04 |
2.7e-41 |
4.27e-01 |
25 |
All-tests volcano plot
