ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:09 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 135


Drug details and screening numbers

Drug Name: Gemcitabine
Drug ID: 135
Synonyms: LY-188011
Brand name: Gemzar
Target: DNA replication

Number of cell lines screened: 870
Screening concentration range(s): 0.004 to 1.024 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a131

EWSR1-FLI1_mut

135

1

1

Gemcitabine

DNA replication

17

850

0.0237

-2.27

-4.65

-2.37

0.88 .

0.88 .

1.1 *

2.54e-05

2.71e-08

1.33e-01

3.2

All-tests volcano plot