ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 140


Drug details and screening numbers

Drug Name: Vinorelbine
Drug ID: 140
Synonyms:
Brand name: Navelbine
Target: Microtubules

Number of cell lines screened: 885
Screening concentration range(s): 0.00025 to 0.064 uM


Statistically significant associations identified = 2

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a222	gain_cnaPANCAN366	140	1	1	Vinorelbine	Microtubules	76	806	-2.75	-3.9	-3.1	0.799	0.49	0.5	0.47	1.14e-04	1.32e-06	9.36e-03	8.5
a445	gain_cnaPANCAN362_(CRNKL1,FOXA2)	140	1	1	Vinorelbine	Microtubules	82	800	-2.75	-3.89	-3.27	0.621	0.38	0.38	0.37	5.7e-04	1.44e-06	9.49e-03	21

All-tests volcano plot