ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 180


Drug details and screening numbers

Drug Name: Thapsigargin
Drug ID: 180
Synonyms:
Brand name:
Target: sarco-endoplasmic reticulum Ca2+-ATPases

Number of cell lines screened: 860
Screening concentration range(s): 0.002 to 0.512 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a275

CHEK2_mut

180

1

1

Thapsigargin

sarco-endoplasmic reticulum Ca2+-ATPases

5

852

-0.669

-3.89

-0.738

3.15

1.6 *

1.6 *

1 *

1.9e-04

3.83e-04

6.87e-02

11

All-tests volcano plot