ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:08 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 193


Drug details and screening numbers

Drug Name: GW-2580
Drug ID: 193
Synonyms: GW-2580
Brand name:
Target: CSF1R (cFMS)

Number of cell lines screened: 924
Screening concentration range(s): 0.078125 to 20 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a127

GNAS_mut

193

1

1

GW-2580

CSF1R (cFMS)

4

917

3

5.29

4.11

-1.18

1.6 *

1.6 *

1.1 *

2.23e-05

1.93e-25

3.44e-01

2.9

All-tests volcano plot