ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 223


Drug details and screening numbers

Drug Name: ZSTK474
Drug ID: 223
Synonyms: KIN001-167
Brand name:
Target: PI3K

Number of cell lines screened: 925
Screening concentration range(s): 0.02 to 5.12 uM and 0.04 to 10.24 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a258

EWSR1-FLI1_mut

223

1

1

ZSTK474

PI3K

17

905

1.63, 2.33

1.03

-0.48

-1.51

0.89 .

0.89 .

0.99 .

1.65e-04

5.76e-40

9.42e-01

11

All-tests volcano plot