ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 281
Drug details and screening numbers
Drug Name: CH5424802
Drug ID: 281
Synonyms:
Brand name:
Target: ALK
Number of cell lines screened: 921
Screening concentration range(s): 0.02 to 5.12 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a186 |
EWSR1-FLI1_mut |
281 |
1 |
1 |
CH5424802 |
ALK |
17 |
901 |
1.63 |
3.67 |
2.58 |
-1.09 |
0.98 . |
0.98 . |
0.93 . |
6.76e-05 |
2.2e-29 |
8.41e-01 |
6 |
a328 |
loss_cnaPANCAN358 |
281 |
1 |
1 |
CH5424802 |
ALK |
20 |
898 |
1.63 |
3.67 |
2.7 |
-0.969 |
0.87 . |
0.91 . |
0.38 |
2.97e-04 |
2.83e-29 |
8.41e-01 |
15 |
a437 |
STAG2_mut |
281 |
1 |
1 |
CH5424802 |
ALK |
21 |
897 |
1.63 |
3.66 |
3.01 |
-0.653 |
0.58 . |
0.6 . |
0.34 |
5.38e-04 |
3.12e-29 |
8.41e-01 |
20 |
All-tests volcano plot
