ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 283


Drug details and screening numbers

Drug Name: GSK2126458
Drug ID: 283
Synonyms: EX-8678
Brand name:
Target: PI3K, MTOR

Number of cell lines screened: 924
Screening concentration range(s): 5e-04 to 0.128 uM and 0.004 to 1.024 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a245

EWSR1-FLI1_mut

283

1

1

GSK2126458

PI3K, MTOR

17

904

-2.0557, 0.0237

-2.92

-4.61

-1.69

0.95 .

0.95 .

0.9 .

1.46e-04

9.76e-29

7.89e-01

9.9

All-tests volcano plot